Microvessel quantitation in invasive breast cancer by staining for factor VIII-related antigen
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چکیده
منابع مشابه
Angiogenesis in urinary bladder carcinoma as defined by microvessel density (MVD) after immunohistochemical staining for Factor VIII and CD31
BACKGROUND Among the patients with bladder cancer, a group is still at risk of disease recurrence, progression, and death from their cancer after curative treatment. Angiogenesis is a crucial pathogenic mechanism for this type of urothelial carcinoma and is a potential therapeutic target. OBJECTIVES To quantify tumor angiogenesis in bladder cancer and determine whether it correlates with tumo...
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A sandwich enzyme immunoassay for plasma factor VIII related antigen has been developed which exploits a para-iodophenol enhanced chemiluminescent reaction to detect the horseradish peroxidase label. The assay entailed 15 min incubations with sample and with conjugate and had a detection limit of 0.12 mU. It showed good within batch precision (coefficient of variation = 2.95-5.8%) and results o...
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Factor VIII related antigen, an endothelial cell product, was markedly raised in systemic necrotising arteritis, reflecting disease activity, but was not raised in active cutaneous vasculitis. In rheumatoid arthritis high levels were only found in systemic vasculitis or Felty's syndrome, but in other connective tissue diseases increased levels were more frequently detected and usually related t...
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A series of 45 lymph nodes involved by Hodgkin's disease have been examined by means of the unlabelled antibody peroxidase-antiperoxidase (PAP) method for the demonstration of factor VIII-related antigen (F VIII R Ag). In addition, five lymph nodes showing reactive follicular hyperplasia were studied. In the specimens of nodular sclerosing Hodgkin's disease, many blood vessels were present, as ...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1995
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1995.251